Abstract: Ordos Basin is a large multicycle superimposed basin, developed on the basement of early Proterozoic crystalline basement. Its evolution progress had undergone four developed stages,i.e. middle-late Proterozoic aulacogen basin , Paleozoic craton basin ,Mesozoic foreland basin and Cenozoic fault-depression basin in its adjacent region. Due to multistages of basin evolution, two series of source rocks and many combinations of reservoir-caprock are developed.With the multicycle of sedimentary structures and formation evolution, superimposed basin has difficulty in exploration, long time needed for exploration, and large potential of exploration. From the regional, natural gas exploration should be focusing on the central-eastern part of Ordos Basin. On the stratum, natural gas exploration should be eyed on the Ordovician weathering crust and upper Paleozoic fluvial-delta reservoirs. With the development of exploration, on the guidance of ideas to deep and to area, west and south of the basin on the area, Cambrian oolitic limestone and Ordovician dolomite rock deposited in the 4th member of Majiagou Formation and dolomite under the sub-salt, will be the new targets of exploration in Ordos Basin.