Abstract: At present, gas well snubbing operation is an important completion and workover technology in the global gas field development, which enables to avoid reservoir damage caused by conventional well killing operation, and has outstanding technical advantages such as reservoir protection, cost reduction and efficiency improvement. In view of the prominent technical problems such as short service life of annulus motive sealing wear-resistant parts in gas well snubbing operation, low pressure grade of inner pipe string sealing tools, and high risk of pipe string flying out and bending, research has been conducted on four aspects, including pressure control technology of annulus motive seal, pressure control technology of inner pipe string sealing, anti-pipe string flying out technology and anti-pressure bending technology. The motive sealing wear-resistant parts with a service life of over 1200m at the wellhead pressure of 35MPa have been developed, as well as the inner pipe string sealing tools at a pressure of 70MPa. The calculation formula of neutralization point and the calculation model of ultimate bending length of pipe strings have been established. The research results have successfully broken through technical bottlenecks such as annular motive sealing and inner pipe string sealing, and formed key technology of gas well snubbing operation, which have been applied for more than 1000 wells in PetroChina Changning-Weiyuan, Changqing Oilfield and Sinopec Fuling blocks, greatly improving the technical capability and efficiency of snubbing operation in gas wells, and obtaining significant results of production increase. The research shows that the key technology of gas well snubbing operation provides powerful technical support for conventional gas well workover and large-scale completion of shale gas wells.