Abstract: The integrated technology of geological engineering in south Sichuan shale gas not only successfully solved the engineering challenges under complex geological conditions, but also significantly increased the production and EUR per well. This paper summarizes the basic concept, core connotation and technical system of the integration of geological engineering of shale gas in southern Sichuan, and puts forward the cultivation method of high production well suitable for different blocks and different conditions. The results show that: (1) the integrated technical system of geological engineering provides important decision-making basis and guidance for the scheme design and on-site implementation of shale gas wells in the whole life cycle, and effectively solves the bottleneck problems of "pressure channeling" and "casing deformation". The casing deformation and pressure channeling rate in Luzhou block are reduced by 19% and 31%. (2) Continuous iterative updating of geological engineering feature understanding and integrated model can significantly improve the accuracy, reliability, consistency and effectiveness of the design; (3) The implementation of the integrated high-yield well cultivation method of geological engineering can significantly increase the production of a single well, among which the average EUR of wells in Changning block increased to 1.30×10⁸m³, an increase of 26.2%; The average EUR of wells in the western Chongqing block increased to 1.53×10⁸m³, an increase of 36%. This method has been applied to different shale gas blocks in southern Sichuan, and remarkable results have been achieved, which verifies the importance of this method in improving the production and economic benefits of a single well, and can also provide reference for the economies of scale development of unconventional oil and gas reservoirs at home and abroad.