Abstract: The geological structure is complicated in the eastern peripheral region of Junngar Basin. Only a few studies were focused on exploration of the region. The quality of 2D seismic data was poor. Synthetic seismograms, geological outcrop, seismic characteristics, interval velocity and non-seismic data were used to identify the geological level of 2D seismic data in the study region. Based on the regional structural background, the paper makes description of the main faults in the region. The interpretation of 2D seismic data shows that the eastern peripheral region of Junggar Basin is in the pattern of a ^“chessboard^” structure, with development of structural elements, such as sag zone, foothill zone and uplift zone. The scope of Shiqiantan sag and Mulei sag is revised, enlarging the area and identifying the scope of Qitaizhuang foothill zone. The current sags in the study region are Middle Paleozoic remained sags. The formations of sag zone and foothill zone developed in the region with the thin remained formations in the uplift zone. The multi-element calibration can help identify the geological level and be used for interpretation of 2D seismic data for the area where exploration degree is low and no exploration well is drilled.