Abstract: Sandstone in tight gas reservoirs changes rapidly. At present, static seismic, cores, logging and other data are used to investigate sandstone distribution. However, due to insufficient seismic data in initial exploration and development, the prediction accuracy of sandstone distribution is low, and it is risky to guide later fracturing design using the results. According to the 4D microseismic fracture monitoring results recorded in more than 30 tight gas wells in a block in the eastern Ordos Basin, the direction and boundary of sandstone distribution in target layers to be fractured were corrected, the risk of sand plugging was predicted according to the sandstone position, and 20-30m3 sand addition schemes were proposed. The study results show that the scale of sandstone distribution greatly affects the fracturing and extension of induced fractures; first, sandstone distribution can be judged by the fracturing monitored by 4D microseismic survey; then, the understanding of sandstone distribution can be constrained from sedimentary facies study; and finally, fracturing parameters can be optimized for accurately locating sand plugging and supporting fracturing design and development of tight gas reservoirs.